Abstract:
Without doubts, the discover of the scutoid, as the geometric solution given by nature to cells in order to allow epithelial tissues to fold, is a clear example of a hug between mathematics and cellular biology. And the story of that discover started thanks to the work in math popularization by Dr. Grima. Thanks to that work, Dr Escudero (a biologist) contacted her and Dr. Márquez (two mathematicians) asking to help him in his research. That was, the initial hug, but more people joinned them and finally it was necessary the help of computer scientifics (doing, amog other things a very needed work as “bridges” between different disciplines) and physicists.
(Imagen de Raquel Gu.)
Researchers: Luis M. Escudero, Clara Grima, Alberto Márquez
Partners: IBIS, Universidad de Sevilla, Universidad Pablo de Olavide, Lehigh University
Related projects:
- Análisis Realista de la Auto-Organización Epitelial en Tres Dimensiones (PID2019-103900GB-I00– Equipo de Investigación)
- Dinámica y biofísica de los escutoides durante la morfogénesis epitelial. (P18-FR-631– Equipo de Investigación)
- Estructura Topológica Epitelial Durante el Desarrollo y al Comienzo de la Formación de un Tumor (BFU2016-74975-P– Equipo de Investigación)
iMAT research line: RL2. Modeling Biological Systems & Health
Highlighted publication: Scutoids are a geometrical solution to three-dimensional packing of epithelia
